1. Nā Waiwai Kino Kemika
ʻAkika BenzoicʻO ka (benzenecarboxylic acid) ka waikawa ʻala maʻalahi loa me ka acidity nāwaliwali (dissociation constant 4.20). He mea hoʻoheheʻe iki ia i ka wai akā hiki ke hoʻoheheʻe maʻalahi i nā mea hoʻoheheʻe organik e like me ka ethanol. Ma muli o kona lipophilicity ikaika, hiki iā ia ke komo i loko o nā membrane cell microbial a hoʻokō i nā hopena antibacterial ma ke kāohi ʻana i ka lawe ʻana o ka waikawa amino, hoʻopilikia i ka hana enzyme hanu, a pale i nā hopena condensation acetyl-CoA.

2. ʻAntimicrobial SpectrumLoaʻa ka hopena e kūʻē i nā bacteria, nā ʻōpala, a me nā mea hū, me nā hopena mālama i hoʻonui ʻia i nā wahi waikawa (e laʻa, ke hoʻololi ʻia i nā paʻakai benzoate).

3. Metabolism a me ka Palekana

I loko o nā holoholona, ​​hoʻopili nui ʻia ka waikawa benzoic i loko o ke akepaʻa, me ka ʻoi aku o 85% i hoʻokuʻu ʻia i loko o ka mimi ma ke ʻano he waikawa hippuric, me ka waiho ʻole ʻana i ke koena a ʻaʻole hoʻi e hoʻopilikia i ke kaulike waikawa-kumu.
Hōʻike nā kānaka a me nā puaʻa i nā ala metabolic like, me ka hoʻopau piha ʻana i loko o 24 mau hola, e hōʻike ana i ka palekana kiʻekiʻe.

II. Nā Hoʻohana Kūikawā ma ka Hānai

Nā Rula a me nā Kūlana Dosage

EUMai ka makahiki 2003, ua ʻae ʻia ka benzoic acid ma ke ʻano he acidifier i ka hānai puaʻa ma 0.5% ~ 1.0%.
KinaUa helu ʻia ma ke ʻano he mea hoʻoponopono pH a me ka mea mālama i loko o kaPapa Inoa Hoʻohui Hānai (2013), me ka ʻole o nā palena dosage akā e pili ana i nā kūlana meaʻai o 0.2 ~ 1.0 g/kg.

Nā Hana a me ka Pono

Koho ʻē aʻe no ka lāʻau antibioticMa hope o ka pāpā ʻana o ka EU i nā lāʻau antibiotic i ka makahiki 2006, ua lilo ka benzoic acid i mea pani nui ma muli o kona mau waiwai antimicrobial ākea, ʻoi aku hoʻi i ka pale ʻana i ka maʻi diarrhea ma hope o ka weaning (PWD) a me ka hoʻonui ʻana i ka ulu ʻana o ka puaʻa.
Ka Hana o ka Ulu ʻanaUa hōʻike ʻia nā noiʻi e hoʻomaikaʻi ana ka hoʻohui ʻana i ka 0.5% benzoic acid i ka ʻai ʻana i ka meaʻai a me ka loaʻa ʻana o ke kaumaha o nā puaʻa i hoʻopau ʻia i ka waiū.

Hoʻohālikelike me nā mea hoʻohui ʻē aʻe

Ke hoʻohālikelike ʻia me ka potassium diformate, ʻoi aku ka wikiwiki o ka omo ʻana o ka benzoic acid i loko o ka foregut a koi ʻia ka ʻenehana uhi e hana ma ka hindgut, ʻoiai ʻo ka potassium diformate e kuhikuhi pololei ana i ka duodenum, e hāʻawi ana i ka pono antimicrobial kiʻekiʻe.