ʻĀpanaUa mālama ʻia ka hoʻokolohua e aʻo i nā hopena o ka diludine i ka hoʻomoe ʻana a me ka maikaʻi o ka hua manu i nā moa a me ka hoʻokokoke ʻana i ke ʻano o nā hopena ma ka hoʻoholo ʻana i nā indexes o nā hua manu a me nā ʻāpana serum 1024 ROM hens ua māhele ʻia i ʻehā mau pūʻulu i loaʻa i ʻehā mau replika o 64 hens kēlā me kēia. d. Penei ka hopena. ʻO ka hoʻohui ʻana i ka diludine i ka meaʻai i hoʻomaikaʻi i ka hana hoʻomoe ʻana o nā moa, ʻo ia ka 150 mg/kg lapaʻau maikaʻi loa; Ua hoʻonui ʻia ka nui o ka waiho ʻana e 11.8% (p<0.01), ua hoʻemi ʻia ka huli ʻana o ka hua manu e 10.36% (p<0 01). Ua hoʻonui ʻia ka paona hua me ka hoʻonui ʻia o ka diludine. Ua hoʻemi nui ka Diludine i ka nui o ka serum o ka uric acid (p<0.01); ʻO ka hoʻohui ʻana i ka diludine i hōʻemi nui i ka serum Ca²⁺a me ka maʻiʻo phosphate inorganic, a me ka hoʻonui ʻana i ka hana o ka alkine phosphatase (ALP) o ka serum (p<0.05), no laila ua loaʻa nā hopena koʻikoʻi i ka hōʻemi ʻana i ka haki ʻana o ka hua manu (p<0.05) a me ka abnormality (p <0.05); Ua hoʻonui nui ka diludine i ke kiʻekiʻe albumen. ʻO ka waiwai Haugh (p <0.01), ka mānoanoa o ka pūpū a me ke kaumaha o ka pūpū (p<0.05), 150 a me 200mg/kg diludine i hoʻemi pū i ka nui o ka cholesterol i loko o ka hua manu (p<0 05), akā ua hoʻonui ʻia ke kaumaha o ka hua manu (p <0.05). Eia kekahi, hiki i ka diludine ke hoʻoikaika i ka hana o ka lipase (p <0.01), a hoʻemi i ka ʻike o ka triglyceride (TG3) (p<0.01) a me ka cholesterol (CHL) (p<0 01) i loko o ka serum, ua hoʻemi ʻia ka pākēneka o ka momona o ka ʻōpū (p<0.01) a me ka momona o ka ate (p<0.01), hiki ke pale i ka momona o ka ʻōpū (p<0.01). Ua hoʻonui nui ka Diludine i ka hana o SOD i ka serum (p<0 01) i ka wā i hoʻohui ʻia ai i ka meaʻai no ka ʻoi aku o 30d. Akā naʻe, ʻaʻohe ʻokoʻa koʻikoʻi i ʻike ʻia i nā hana o GPT a me GOT o ka serum ma waena o ka mana a me ka hui mālama ʻia. Ua manaʻo ʻia he hiki i ka diludine ke pale i ka membrane o nā cell mai ka hoʻonā ʻana

ʻōlelo nuiDiludine; moa; SOD; cholesterol; triglyceride, lipase

 

ʻO ka diludine ka mea hou non-nutritive anti-oxidation vitamin additive a loaʻa nā hopena^[1-3]no ka hoʻopaʻa ʻana i ka oxidation o ka membrane biological a me ka hoʻopaʻa ʻana i ke kino o nā cell biological, etc.^[4]no ka paipai ʻana i ka ulu ʻana o ka moa a me ke kūʻē ʻana i ka hau a me ka ʻelemakule no kekahi mau mea kanu. Ua hōʻike ʻia ʻaʻole hiki i ka diludine ke hoʻoikaika i ka ulu ʻana o ka holoholona, ​​​​akā e hoʻomaikaʻi i ka hana hānau ʻana o nā holoholona me ka maopopo a hoʻomaikaʻi i ka nui o ka hāpai ʻana, ka hoʻopuka ʻana o ka waiū, ka hua manu a me ka helu hatching o ka holoholona wahine.^{[1, 2, 5-7]}. Ua hoʻomaka ʻia ke aʻo ʻana i ka diludine ma Kina mai ka makahiki 1980, a ʻo ka hapa nui o nā noiʻi e pili ana i ka diludine ma Kina ua paʻa i ka hoʻohana ʻana i ka hopena a hiki i kēia manawa, a ua hōʻike ʻia nā hoʻāʻo liʻiliʻi o ka hoʻomoe manu. Ua hōʻike ʻo Chen Jufang (1993) e hiki i ka diludine ke hoʻomaikaʻi i ka puka o ka hua manu a me ke kaumaha o ka hua manu, akā ʻaʻole i hohonu.^[5]ke aʻo ʻana i ke ʻano hana o ia mea. No laila, ua hoʻokō mākou i ke aʻo ʻōnaehana o ka hopena a me ka hana o ia mea ma ka hānai ʻana i nā moa hoʻomoe me ka meaʻai doped me ka diludine, a ua hōʻike ʻia kekahi hapa o ka hopena i kēia manawa:

Papa 1 Ka hoʻohui ʻana a me nā mea momona o ka ʻai hoʻokolohua

%

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Ka hoʻohui ʻana o ka meaʻai Mea ʻai meaʻai

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Kāna 62 ME③ 11.97

ʻO ka pīni pulu 20 CP 17.8

ʻAi iʻa 3 Ca 3.42

ʻAi rapeseed 5 P 0.75

ʻAi iwi 2 M a me 0.43

ʻAi pōhaku 7.5 M a me Cys 0.75

Methionine 0.1

Paakai 0.3

Multivitamin① 10

Nā mea ʻimi ② 0.1

-----------------------------------------------------------------------------------

① Multivitamin: 11mg o riboflavin, 26mg o ka folic acid, 44mg o ka oryzanin, 66mg o ka niacin, 0.22mg o biotin, 66mg o B6, 17.6ug o B12, 880mg o choline, 30mg o VK, V 66IU o_E, 6600ICU o V_Da me 20000ICU o V_A, hoʻohui ʻia i kēlā me kēia kilokani o ka meaʻai; a hoʻohui ʻia ka 10g multivitamin i kēlā me kēia 50kg o ka meaʻai.

② Nā mea hoʻoheheʻe (mg/kg): 60 mg o Mn, 60mg o Zn, 80mg o Fe, 10mg o Cu, 0.35mg o I a me 0.3mg o Se i hoʻohui ʻia i kēlā me kēia kilokani o ka meaʻai.

③ ʻO ka ʻāpana o ka ikehu metabolizable e pili ana iā MJ/kg.

 

1. Nā mea hana a me ke ʻano

1.1 Mea ho'āʻo

ʻO Beijing Sunpu Biochem. & ʻenehana. Pono ʻo Co., Ltd. e hāʻawi i ka diludine; a e pili ana ka holoholona hoao i na moa hoomoe kalepa Roma he 300 la.

 

ʻAi hoʻāʻo: pono e hoʻomākaukau ʻia ka meaʻai hoʻokolohua e like me ke kūlana maoli i ka wā o ka hana ʻana ma ke kumu o ka maʻamau NRC, e like me ka hōʻike ʻana ma ka Papa 1.

1.2 Hana ho'āʻo

1.2.1 Hoʻokolohua hānai: pono e hoʻokō ʻia ka hoʻokolohua hānai ma ka mahiʻai o Hongji Company ma Jiande City; 1024 Pono e koho ʻia nā moa hoʻomoe Roma a māhele ʻia i ʻehā mau pūʻulu ma ke ʻano he 256 mau ʻāpana (pono e hana hou ʻia kēlā me kēia hui no ʻehā manawa, a ʻo kēlā me kēia moa he 64 manawa); pono e hānaiʻia nā moa me nā meaʻaiʻehā me nā mea likeʻole o ka diludine, a me 0, 100, 150, 200mg / kg o nā meaʻai e hoʻohuiʻia no kēlā me kēia hui. Ua hoʻomaka ka hoʻokolohua ma ʻApelila 10, 1997; a hiki i na moa ke loaa ka ai a lawe wale i ka wai. Pono e hoʻopaʻa ʻia ka meaʻai i lawe ʻia e kēlā me kēia pūʻulu, ka helu hoʻomoe, ka hoʻopuka ʻana o ka hua manu, ka hua haʻi a me ka helu o nā hua manu ʻino. Eia kekahi, ua pau ka hoʻāʻo ʻana ma Iune 30, 1997.

1.2.2 Ana o ka maikaʻi hua: 20 hua pono e lawe randomly i ka wā i hoʻokō 'ia ai ka ho'āʻo 'ehā 40 lā i mea e ana i na mea hoailona e pili ana i ka hua hua, e like me ka hua hua hua helu helu, haugh wae, pili kaumaha o ka pūpū, ka mānoanoa o ka iwi, ka yolk index, ke kaumaha pili o ka yolk, etc. hana ʻia e Ningbo Cixi Biochemical Test Plant.

1.2.3 Ana o ka serum biochemical index: 16 mau moa hoao mai kela hui keia manawa i ka hoao ana no 30 la a i ka pau ana o ka hoao ana e hoomakaukau i ka serum ma hope o ka laʻana o ke koko mai ka vein ma ka eheu. Pono e mālama ʻia ka serum ma kahi haʻahaʻa haʻahaʻa (-20 ℃) ​​no ke ana ʻana i nā kuhikuhi biochemical pili. Pono e ana ʻia ka pākēneka o ka momona o ka ʻōpū a me ka lipid ate ma hope o ka pepehi ʻana a me ka lawe ʻana i ka momona o ka ʻōpū a me ke ake i ka pau ʻana o ke koko.

Pono e ana ʻia ka superoxide dismutase (SOD) me ka hoʻohana ʻana i ke ʻano saturation i mua o ka pahu reagent i hana ʻia e ka Beijing Huaqing Biochem. & ʻenehana. Keʻena noiʻi. Pono e ana ʻia ka ʻakika uric (UN) i loko o ka serum me ka hoʻohana ʻana i ke ʻano U ricase-PAP i mua o ke kit reagent Cicheng; pono e ana i ka triglyceride (TG3) me ka hoʻohana ʻana i ke ʻano GPO-PAP hoʻokahi ʻanuʻu i mua o ka pahu Cicheng reagent; pono e ana i ka lipase ma ka hoohana ana i ka nephelometry ma ke alo o ka Cicheng reagent kit; Pono e ana i ka serum total cholesterol (CHL) me ka hoʻohana ʻana i ke ʻano COD-PAP i mua o ka pahu Cicheng reagent; pono e ana i ka glutamic-pyruvic transaminase (GPT) me ka hoohana ana i ka colorimetry ma ke alo o ka Cicheng reagent kit; pono e ana i ka glutamic-oxalacetic transaminase (GOT) me ka hoʻohana ʻana i ka colorimetry i mua o ka pahu Cicheng reagent; pono ke ana 'ia ka alkaline phosphatase (ALP) me ka hoohana ana i ke kaina helu ma ke alo o ka pahu reagent Cicheng; ka iona calcium (Ca²⁺) i loko o ka serum e pono ke ana ma ka hoʻohana ʻana i ka methylthymol blue complexone me ke ʻano o ke ʻano o ka Cicheng reagent kit; pono e ana i ka phosphorus inorganic (P) me ka hoohana ana i ke ano polu molybdate ma ke alo o ka pahu hoohuoi Cicheng.

 

2 Ka hopena ho'āʻo

2.1 Ka hopena i ka hana ʻana

Hōʻike ʻia nā hana hoʻomoe o nā hui like ʻole me ka hoʻohana ʻana i ka diludine ma ka Papa 2.

Papa 2 Hana ʻia nā moa i hānai ʻia me ka ʻai kumu i hoʻohui ʻia me nā pae ʻehā o ka diludine

 

Ka nui o ka diludine e hoʻohui ʻia (mg/kg)
	0	100	150	200
ʻai ʻai (g)
Ka helu kau ʻana (%)
ʻAwelika kaumaha o ka hua (g)
Lakiō o ka mea me ka hua
Ka helu o ka hua manu nahaha (%)
Ka helu o ka hua manu ʻokoʻa (%)

 

Mai ka Papa 2, ua hoʻomaikaʻi maikaʻi ʻia nā helu kau ʻana o nā hui āpau i hoʻohana ʻia ma ka hoʻohana ʻana i ka diludine, kahi i ʻoi aku ka maikaʻi o ka hopena ke hoʻohana ʻia me ka hoʻohana ʻana i ka 150mg/kg (a hiki i ka 83.36%), a ua hoʻomaikaʻi ʻia ka 11.03% (p<0.01) i hoʻohālikelike ʻia me ka hui kuhikuhi; no laila ka diludine ka hopena o ka hoʻomaikaʻi ʻana i ka helu kau. ʻIke ʻia mai ka awelika kaumaha o ka hua, ke piʻi nei ke kaumaha o ka hua (p>0.05) me ka hoʻonui ʻana i ka diludine i ka ʻai i kēlā me kēia lā. Ke hoʻohālikelikeʻia me ka hui kuhikuhi,ʻaʻole maopopo kaʻokoʻa ma waena o nā'āpana hana a pau o nā hui i hoʻohanaʻia ma ka hoʻohanaʻana i ka 200mg / kg o ka diludine i ka manawa e hoʻonuiʻia ai ka 1.79g o ka meaʻai hānai; akā naʻe, ʻike mālie ʻia ka ʻokoʻa me ka piʻi ʻana o ka diludine, a ʻo ka ʻokoʻa o ka ratio o ka mea me ka hua manu ma waena o nā ʻāpana i hana ʻia (p<0.05), a ʻoi aku ka maikaʻi o ka hopena inā 150mg/kg o diludine a he 1.25:1 i hoʻemi ʻia no 10.36% (p<0.01) i hoʻohālikelike ʻia me ka hui kuhikuhi. ʻIke ʻia mai ka helu haʻihaʻi o nā ʻāpana a pau i hana ʻia, hiki ke hoʻemi ʻia ka helu haʻihaʻi (p<0.05) ke hoʻohui ʻia ka diludine i ka ʻai i kēlā me kēia lā; a ua ho'emi 'ia ka pakeneka o nā hua ma'amau (p<0.05) me ka ho'onui 'ana i ka diludine.

 

2.2 Ka hopena i ka maikaʻi o ka hua

ʻIke ʻia ma ka Papa 3, ʻaʻole pili ka huaʻōlelo hua manu a me ka ʻumekaumaha kikoʻī o ka hua (p>0.05) ke hoʻohui ʻia ka diludine i ka meaʻai i kēlā me kēia lā, a hoʻonui ʻia ke kaumaha o ka pūpū me ka hoʻonui ʻana i ka diludine i hoʻohui ʻia i ka meaʻai i kēlā me kēia lā, kahi e hoʻonui ʻia ai nā paona o nā pūpū no 10.58% a me 10.85% (p<0.05) ke hoʻohālikelike ʻia me ka 10.85% (p<0.05). Hoʻohui ʻia ka 200mg / kg o diludine; hoʻonui ʻia ka mānoanoa o ka pūpū hua ma ka hoʻonui ʻana i ka diludine i ka meaʻai i kēlā me kēia lā, kahi e hoʻonui ʻia ai ka mānoanoa o ka pūpū hua no 13.89% (p<0.05) ke hoʻohui ʻia ka 100mg/kg o ka diludine e hoʻohālikelike ʻia me nā hui kuhikuhi, a hoʻonui ʻia ka mānoanoa o nā pūpū hua manu no 19.44% (p<0.0.1) (p<0.0.7) i kēlā me kēia manawa Hoʻohui ʻia ka 150 a me 200mg / kg. Hoʻomaikaʻi ʻia ka ʻāpana Haugh (p<0.01) i ka wā e hoʻohui ʻia ai ka diludine, e hōʻike ana he hopena ko ka diludine e hāpai i ka hoʻohui ʻana o ka albumen mānoanoa o ka hua keʻokeʻo. ʻO ka diludine ka hana o ka hoʻomaikaʻi ʻana i ka index of yolk, akā ʻaʻole maopopo ka ʻokoʻa (p<0.05). He ʻokoʻa nā mea i loko o ka cholesterol o ka hua manu o nā hui āpau a hiki ke hoʻemi ʻia (p<0.05) ma hope o ka hoʻohui ʻana i 150 a me 200mg/kg o diludine. ʻOkoʻa nā paona pili o ka hua manu mai kekahi i kekahi ma muli o nā nui like ʻole o ka diludine i hoʻohui ʻia, kahi e hoʻomaikaʻi ʻia ai nā paona pili o ka hua manu no 18.01% a me 14.92% (p<0.05) ke hoʻohālikelike ʻia ka 150mg/kg a me 200mg/kg me ka hui kuhikuhi; No laila, ʻo ka diludine kūpono ka hopena o ka hoʻoikaika ʻana i ka synthesis o ka hua manu.

 

Papa 3 Nā hopena o ka diludine i ka maikaʻi o ka hua

Ka nui o ka diludine e hoʻohui ʻia (mg/kg)
ʻAno hua	0	100	150	200
Helu hua manu (%)
Kaumaha kiko hua (g/cm3)
Kaumaha pili o ka iwi hua manu (%)
ʻO ka mānoanoa o ka ʻili hua manu (mm)
ʻĀpana Haugh (U)
Helu huaʻai hua manu (%)
Cholesterol o ka hua manu (%)
Kaumaha pili o ka hua hua manu (%)

 

2.3 Nā hopena i ka pākēneka momona o ka ʻōpū a me ka momona o ke ake o nā moa hoomoe.

E nānā i ka Kiʻi 1 a me ka Kiʻi 2 no nā hopena o ka diludine i ka pākēneka momona o ka ʻōpū a me ka maʻi o ka momona o ke ake o nā moa hoʻomoe.

 

 

 

Helu 1 Ka hopena o ka diludine ma ka pakeneka o ka momona o ka opu (PAF) o na moa hoomoe.

 

	Pākēneka o ka momona o ka ʻōpū
	Ka nui o ka diludine e hoʻohui ʻia

 

 

Kiʻi 2 Ka hopena o ka diludine i ka momona o ke akepaʻa (LF) o nā moa hoʻomoe

	ʻO ka momona o ka ate
	Ka nui o ka diludine e hoʻohui ʻia

ʻIkeʻia mai ka Figure 1, ua ho'ēmiʻia nā pākēneka o ka momona o ka'ōpū o ka hui ho'āʻo no 8.3% a me 12.11% (p<0.05) i ka wā e hoʻemiʻia ai ka 100 a me 150mg / kg o ka diludine me ka hui kuhikuhi, a me ka pakeneka o ka momona o ka'ōpū i ho'ēmiʻia no 33.49% o ka diludine (p<0.49%). hoʻohui ʻia. ʻIke ʻia mai ka Figure 2, ua hoʻemi ʻia nā mea momona o ka ate (maloʻo loa) i hana ʻia e 100, 150, 200mg/kg o diludine i kēlā me kēia no 15.00% (p<0.05), 15.62% (p<0.05) a me 27.7% (p<0.01); No laila, ʻo ka diludine ka hopena o ka hoʻemi ʻana i ka pākēneka o ka momona o ka ʻōpū a me ka momona o ke akepaʻa o ka waiho ʻana i ʻike maopopo ʻia, kahi maikaʻi loa ka hopena ke hoʻohui ʻia ka 200mg / kg o diludine.

2.4 Ka hopena i ka helu helu biochemical serum

ʻIke ʻia mai ka Papa 4, ʻaʻole maopopo ka ʻokoʻa ma waena o nā ʻāpana i hana ʻia i ka Phase I (30d) o ka hoʻāʻo SOD, a ʻoi aku ka kiʻekiʻe o nā kuhikuhina biochemical serum o nā hui āpau i hoʻohui ʻia ka diludine i ka Phase II (80d) o ka hoʻāʻo ma mua o ka hui kuhikuhi (p<0.05). Hiki ke hoʻemi ʻia ka uric acid (p<0.05) i ka serum ke hoʻohui ʻia ka 150mg/kg a me 200mg/kg o diludine; ʻoiai ka hopena (p<0.05) i ka wā e hoʻokomoʻia ai ka 100mg / kg o ka diludine i ka Phase I. Hiki i ka diludine ke hoʻemi i ka triglyceride i loko o ka serum, kahi iʻoi aku ka maikaʻi o ka hopena (p<0.01) i ka hui ke hoʻokomoʻia ka 150mg / kg o ka diludine i ka Phase I, aʻoi aku ka maikaʻi ma ka hui i ka 200mg / kg i hoʻohuiʻia i ka Phaseludine. Hoʻemi ʻia ka nui o ka cholesterol i loko o ka serum me ka hoʻonui ʻana i ka diludine i hoʻohui ʻia i ka meaʻai i kēlā me kēia lā, ʻoi aku ka nui o ka nui o ka cholesterol i loko o ka serum e hoʻemi ʻia no 36.36% (p<0.01) a me 40.74% (p<0.01) i kēlā me kēia manawa ke hoʻohui ʻia ka 150mg/kg a me 200mg/kg o ka diludine me ka reference 6% no ka hui. (p<0.01), 37.40% (p<0.01) a me 46.66% (p<0.01) i ka wā i hoʻohui ʻia ai ka 100mg/kg, 150mg/kg a me 200mg/kg o diludine i ka Phase II i hoʻohālikelike ʻia me ka hui kuhikuhi. Eia kekahi, ua hoʻonui ʻia ka ALP me ka hoʻonui ʻana i ka diludine i hoʻohui ʻia i ka ʻai i kēlā me kēia lā, ʻoiai ʻoi aku ka kiʻekiʻe o nā waiwai o ka ALP i loko o ka hui i hoʻohui ʻia ʻo 150mg/kg a me 200mg/kg o diludine ma mua o ka hui kuhikuhi (p<0.05).

Papa 4 Nā hopena o ka diludine ma nā ʻāpana serum

Ka nui o ka diludine e hoʻohui ʻia (mg/kg) ma ka Māhele I (30d) o ka hoʻāʻo
'ikamu	0	100	150	200
Superoxide dismutase (mg/mL)
ʻakika uric
Triglyceride (mmol/L)
Lipase (U/L)
Kolekele (mg/dL)
Glutamic-pyruvic transaminase (U/L)
Glutamic-oxalacetic transaminase (U/L)
Alkaline phosphatase (mmol/L)
ʻO ka iona calcium (mmol/L)
phosphorus anoano (mg/dL)

 

Ka nui o ka diludine e hoʻohui ʻia (mg/kg) i ka Phase II (80d) o ka hoʻāʻo
'ikamu	0	100	150	200
Superoxide dismutase (mg/mL)
ʻakika uric
Triglyceride (mmol/L)
Lipase (U/L)
Kolekele (mg/dL)
Glutamic-pyruvic transaminase (U/L)
Glutamic-oxalacetic transaminase (U/L)
Alkaline phosphatase (mmol/L)
ʻO ka iona calcium (mmol/L)
phosphorus anoano (mg/dL)

 

3 Ka nānā 'ana a me ke kūkākūkā

3.1 Ua hoʻomaikaʻi ka diludine i ka hoʻāʻo ʻana i ka helu kau ʻana, ke kaumaha o ka hua manu, ka ʻāpana Haugh a me ke kaumaha pili o ka yolk hua, i hōʻike ʻia i ka diludine nā hopena o ka hoʻoulu ʻana i ka assimilation o ka protein a me ka hoʻomaikaʻi ʻana i ka nui o ka synthesis o ka albumen mānoanoa o ka hua keʻokeʻo a me ka protein o ka yolk hua. Eia hou, ua hoʻemi ʻia ka ʻike o ka uric acid i loko o ka serum; a ua ʻae ʻia ʻo ka hoʻemi ʻana o ka ʻike o ka nitrogen non-protein i loko o ka serum ua hoʻemi ʻia ka wikiwiki catabolism o ka protein, a ua hoʻopaneʻe ʻia ka manawa paʻa o ka nitrogen. Hāʻawi kēia hopena i ke kumu o ka hoʻonui ʻana i ka paʻa ʻana o ka protein, ka hāpai ʻana i ka hoʻomoe ʻana i nā hua a me ka hoʻomaikaʻi ʻana i ke kaumaha o ka hua o nā moa hoʻomoe. Ua hōʻike ʻia ka hopena o ka hoʻāʻo e ʻoi aku ka maikaʻi o ka waiho ʻana i ka wā i hoʻohui ʻia ai ka 150mg/kg o diludine, ʻo ia ka mea i kūlike me ka hopena.^[6,7]ʻO Bao Erqing a me Qin Shangzhi a loaʻa ma ka hoʻohui ʻana i ka diludine i ka wā hope o ka hoʻomoe ʻana i nā moa. Ua hoʻemi ʻia ka hopena inā ʻoi aku ka nui o ka diludine ma mua o 150mg/kg, ʻo ia paha no ka hoʻololi ʻana o ka protein.^[8]Ua hoʻopilikia ʻia ma muli o ka nui o ka dosage a me ka haʻahaʻa nui o ka metabolism o ke kino i ka diludine.

3.2 ʻO ke kuʻina o Ca²⁺i ka serum o ka waiho huamoa ua hoemiia, ka P i ka serum ua hoemiia i ka hoomaka ana a me ka ALP hana i hoonui maopopo i mua o ka diludine, i hoike ia diludine pili i ka metabolism o Ca a me P maopopo. Ua hōʻike ʻo Yue Wenbin e hiki i ka diludine ke hāpai i ka absorption^[9] nā mea mineral Fe a me Zn; Aia ka ALP i loko o nā ʻiʻo, e like me ke ake, ka iwi, ka ʻōpū ʻōpū, ka puʻupaʻa, a pēlā aku; ʻO ka ALP i loko o ka serum mai ke ake a me ka iwi ka nui; Aia ka ALP i ka iwi i ka osteoblast a hiki ke hoʻohui i ka ion phosphate me ka Ca2 mai ka serum ma hope o ka hoʻololi ʻana ma o ka hoʻonui ʻana i ka decomposition o ka phosphate a me ka hoʻonui ʻana i ka ʻike o ka ion phosphate, a waiho ʻia ma ka iwi ma ke ʻano o ka hydroxyapatite, etc. Eia kekahi, ua hōʻemi ʻia ka hapa o ka hua manu i haʻihaʻi ʻia a me ka pākēneka o ka hua manu ma ke ʻano o ka hoʻomoe ʻana, ʻo ia hoʻi ka wehewehe ʻana i kēia wahi.

3.3 Ua hoʻemi ʻia ka momona o ka ʻōpū a me ka momona o ke akepaʻa o nā moa hoʻomoe ma ka hoʻohui ʻana i ka diludine i ka meaʻai, ʻo ia ka mea i hōʻike ʻia i ka diludine ka hopena o ke kāohi ʻana i ka synthesis o ka momona i ke kino. Eia hou, hiki i ka diludine ke hoʻomaikaʻi i ka hana o ka lipase i ka serum i ka wā mua; Ua hoʻonui ʻia ka hana o ka lipase i ka hui i hoʻohui ʻia ai ka 100mg/kg o ka diludine, a ua hoʻemi ʻia nā mea o ka triglyceride a me ka cholesterol i loko o ka serum (p<0.01), kahi i hōʻike ʻia e hiki i ka diludine ke hoʻoikaika i ka decomposition o ka triglyceride a kāohi i ka synthesis o ka cholesterol. Hiki ke kāohi ʻia ka waiho ʻana o ka momona ma muli o ka enzyme o ka lipid metabolism i loko o ke ake^[10,11], a me ka hoemi ana o ka cholesterol ma ka hua huamoa ua wehewehe pu i keia wahi [13]. Ua hōʻike ʻo Chen Jufang e hiki i ka diludine ke kāohi i ka hana ʻana o ka momona i loko o ka holoholona a hoʻomaikaʻi i ka pākēneka ʻiʻo wīwī o nā broilers a me ka puaʻa, a loaʻa iā ia ka hopena o ka mālama ʻana i ka momona momona. Ua akaka ka hopena o ka ho'āʻo ʻana i kēia ʻano hana, a ʻo ka ʻoki ʻana a me ka nānā ʻana o nā moa hoʻāʻo i hōʻike pū ʻia e hiki i ka diludine ke hoʻemi i ka nui o ka ulu ʻana o ka momona o nā moa hoʻomoe.

3.4 ʻO GPT a me GOT nā hōʻailona koʻikoʻi ʻelua e hōʻike ana i nā hana o ke ake a me ka puʻuwai, a hiki ke pohō ke ake a me ka puʻuwai inā kiʻekiʻe nā hana o ia mea. ʻAʻole i hoʻololi ʻia nā hana o GPT a me GOT i ka serum i ka wā i hoʻohui ʻia ai ka diludine i ka hoʻāʻo, i hōʻike ʻia ʻaʻole i hōʻeha ʻia ke ake a me ka puʻuwai; Eia hou, ua hōʻike ʻia ka hopena ana o SOD e hiki ke hoʻomaikaʻi ʻia ka hana o SOD i loko o ka serum i ka wā i hoʻohana ʻia ai ka diludine no kekahi manawa. SOD e pili ana i ka scavenger nui o ka superoxide free radical i loko o ke kino; He mea koʻikoʻi ia no ka mālama pono ʻana o ka membrane biological, hoʻomaikaʻi i ka hiki ke pale i ke kino a mālama i ke olakino o ka holoholona ke hoʻonui ʻia ka ʻike o ka SOD i ke kino. Ua hōʻike ʻo Quh Hai, a pēlā aku, hiki i ka diludine ke hoʻomaikaʻi i ka hana o 6-glucose phosphate dehydrogenase i loko o ka membrane biological a hoʻopaʻa i nā ʻiʻo [2] o ka cell biological. Ua kuhikuhi ʻo Sniedze i ka diludine i kāohi i ka hana [4] o NADPH cytochrome C reductase maopopo ma hope o ke aʻo ʻana i ka pilina ma waena o ka diludine a me ka enzyme pili i ka NADPH kikoʻī electron hoʻololi kaulahao i ka ʻiole ate microsome. Ua kuhikuhi pū ʻo Odydents ua pili ka diludine [4] i ka ʻōnaehana oxidase composite a me ka enzyme microsomal e pili ana me NADPH; a ʻo ke ʻano o ka hana o ka diludine ma hope o ke komo ʻana i loko o ka holoholona e pāʻani i ke ʻano o ka pale ʻana i ka oxidation a me ka pale ʻana i ka membrane biological [8] ma ke kāohi ʻana i ka hana o ka electron transfer NADPH enzyme o ka microsome a me ke kāohi ʻana i ke kaʻina peroxidation o ka pūhui lipid. Ua hōʻike ka hopena hōʻike i ka hana pale o ka diludine i ka membrane biological mai nā loli o ka hana SOD i nā loli o nā hana o GPT a me GOT a hōʻoia i nā hopena noiʻi o Sniedze a me Odydents.

 

Kuhikuhi

1 Zhou Kai, Zhou Mingjie, Qin Zhongzhi, etc. E aʻo i ka diludine o ka hoʻomaikaʻi ʻana i ka hana hānau o nā hipaJ. Mauu aLivestock 1994 (2): 16-17

2 Qu Hai, Lv Ye, Wang Baosheng, ʻO ka hopena o ka diludine i hoʻohui ʻia i ka ʻai i kēlā me kēia lā i ka helu o ka hāpai ʻana a me ka maikaʻi o ka pua o ka ʻiʻo rabbit.J. Ka Nupepa Pake o ka Mahi Lapiti1994(6): 6-7

3 Chen Jufang, Yin Yuejin, Liu Wanhan, a pela aku.Noi Hanai1993 (3): 2-4

4 Zheng Xiaozhong, Li Kelu, Yue Wenbin, etc. Kūkākūkā i ka hopena o ka noi a me ka hana o ka diludine ma ke ʻano he mea hoʻoulu ulu moa.Noi Hanai1995 (7): 12-13

5 Chen Jufang, Yin Yuejin, Liu Wanhan, a me nā mea ʻē aʻe.Noi Hanai1993 (3): 2-5

6 Bao Erqing, Gao Baohua, Ho'āʻo i ka diludine no ka hānai ʻana i ka ʻiole PekingNoi Hanai1992 (7): 7-8

7 Qin Shangzhi Ho'āʻo no ka hoʻomaikaʻi ʻana i ka huahana o nā moa ʻiʻo i ka wā hope o ka waiho ʻana me ka hoʻohana ʻana i ka diludineGuangxi Journal of Animal Husbandry & Veterinary Medicine1993.9(2): 26-27

8 Dibner J Jl Lvey FJ ​​Hepatic protein a me ka amino acid metabolian ma ka moa Sci moa1990.69(7): 1188- 1194

9 Yue Wenbin, Zhang Jianhong, Zhao Peie, a me nā mea ʻē aʻe. E aʻo i ka hoʻohui ʻana i ka diludine a me ka hoʻomākaukau ʻana o Fe-Zn i ka ʻai ʻana i kēlā me kēia lā o nā moa hoʻomoe.Hanai a me na holoholona1997, 18(7): 29-30

10 Mildner A na M, Steven D Clarke Porcine fatty acid synthase cloning o kahi DNA hoʻohui, ka puʻunaue kiko o konamRNA a me ka hoʻopau ʻana i ka ʻōlelo e ka somatotropin a me ka protein meaʻai J Nutri 1991, 121 900

11 W alzon RL Smon C, M orishita T, et a I Fatty liver hemorrhagic syndrome i nā moa i hānai nui ʻia i kahi meaʻai hoʻomaʻemaʻe ʻia nā hana enzyme i koho ʻia a me ka mōʻaukala ate e pili ana i ka hanohano o ke ake a me ka hana hānau.Sci moa,1993 72(8): 1479- 1491

12 Donaldson WE Lipid metabolism ma ke akepaʻa o ka moa pane i ka hānaiSci moa. 1990, 69(7) : 1183- 1187

13 Ksiazk ieu icz J. K ontecka H, ​​H ogcw sk i L He memo no ka cholesterol koko ma ke ano he hoailona o ka momona o ke kino o na pakeke.Nūpepa o Aninal a me ka ʻepekema hānai,1992, 1(3/4): 289- 294