Ke pāpā mālie ʻia nei nā huahana antibiotic like ʻole i ka hana manu a puni ka honua ma muli o nā pilikia maikaʻi ʻole e pili ana i nā koena antibiotic a me ke kūʻē ʻana i ka antibiotic. ʻO Tributyrin kahi koho kūpono i nā antibiotics. Ua hōʻike nā hopena o ke aʻo ʻana i kēia manawa e hiki i ka tributyrin ke hoʻomaikaʻi i ka hana ulu ʻana ma o ka hoʻololi ʻana i nā ʻōkuhi biochemical koko a me ka haku mele microflora cecal o nā broilers hulu melemele. I ka ʻike maikaʻi loa o mākou, ua noiʻi kekahi mau haʻawina i nā hopena o ka tributyrin ma ka microbiota ʻōpū a me kona pilina me ka hana ulu ʻana i nā broilers. E hāʻawi kēia i kahi kumu ʻepekema no ka hoʻohana ʻana o tributyrin i ka mahi holoholona i kēia au ma hope o ka antibiotic.

Hoʻopuka ʻia ka waikawa butyric i loko o ka lumen ʻōpū holoholona ma o ka fermentation bacteria o nā kalapona ʻai i hoʻoheheʻe ʻole ʻia a me nā protein endogenous. 90% o kēia waikawa butyric i hoʻopili ʻia e nā cell epithelial cecal a i ʻole colonocytes e hāʻawi i nā hopena maikaʻi he nui i ke olakino ʻōpū.

Eia nō naʻe, he ʻala ʻino ko ka waikawa butyric manuahi a he paʻakikī ke lawelawe ʻana i ka hana. Eia kekahi, ua hōʻike ʻia ua komo nui ʻia nā waikawa butyric manuahi i loko o ke ala gastro-intestinal kiʻekiʻe, e hopena ana i ka hapa nui ʻaʻole e hiki i ka ʻōpū nui, kahi e hoʻokō ai ka waikawa butyric i kāna hana nui.

No laila, ua hoʻomohala ʻia ka sodium salt butyrate kalepa e hoʻomaʻalahi i ka lawelawe ʻana a pale i ka hoʻokuʻu ʻana o ka waikawa butyric i loko o ke ala gastro-intestinal kiʻekiʻe.

Akā, ʻo ka tributyrin he butyric acid a me ka mono-butyrin a ma ke ala ʻōpū o luna, ua hoʻoheheʻe ʻia ʻo tributyrin i butyric acid a me α-mono-butyrin akā ma ka ʻōpū hope, ʻo ka molekala nui ʻo α-monobutyrin ka mea e hāʻawi ana i ka ikehu hou aʻe, e hoʻoikaika i ka ulu ʻana o nā ʻiʻo a e paipai i ka ulu ʻana o ke capillary no ka lawe ʻana i nā meaʻai maikaʻi aʻe.

Aia kekahi mau maʻi e pili ana i ke olakino o ka ʻōpū o ka moa, e like me:

• ka maʻi pākī
• ka maʻi malabsorption
• ka maʻi ʻaʻai koko
• ʻōpū necrotic

Ua hoʻohana nui ʻia ka hoʻohui ʻana o ka tributyrin e hakakā i nā maʻi ʻōpū, a i ka hopena e hoʻomaikaʻi i ke olakino ʻōpū moa.

I loko o nā moa wahine hoʻomoe, hiki iā ia ke hoʻomaikaʻi i ka omo ʻana o ka calcium ma ke ʻano nui i nā moa wahine hoʻomoe kahiko a hoʻomaikaʻi i ka maikaʻi o nā pūpū hua.

I nā puaʻa puaʻa liʻiliʻi, he wā koʻikoʻi ka hoʻololi ʻana i ka waiū umauma ma muli o ke kaumaha nui ma muli o ka neʻe ʻana mai ka meaʻai wai a i ka meaʻai paʻa, ka loli ʻana o ke kaiapuni, a me ka hui pū ʻana me nā hoa pā hou.

Ma kahi hoʻokolohua puaʻa liʻiliʻi i hana ʻia ma Rivalea, ua hōʻike maopopo ʻia ʻo ka hoʻohui ʻana i 2.5 kg Tributyrin /MT i nā meaʻai ma hope o ka weaning no 35 mau lā ua hoʻomaikaʻi i ka piʻi ʻana o ke kaumaha o ke kino ma 5% a me ka lakio hoʻololi hānai ma 3 mau helu.

Hiki ke hoʻohana ʻia ʻo Tributyrin i ka waiū ma ke ʻano he pani no ka waiū holoʻokoʻa a hōʻole hapa i ka hopena maikaʻi ʻole o nā mea pani waiū i ka ulu ʻana o ka rumen.