Ua noiʻi ʻia ka hoʻololi hapa ʻana o ka palaoa iʻa me ka palaoa soybean (SBM) ma ke ʻano he koho hoʻomau a hoʻokele waiwai i loko o kekahi mau ʻano mahiʻai a me nā mea kanu i hoʻolālā ʻia no ke kālepa ʻana, me ka iʻa ʻōniʻoniʻo wai maʻemaʻe (ʻO Oncorhynchus mykiss). Eia nō naʻe, loaʻa i ka soy a me nā mea kanu ʻē aʻe nā pae kiʻekiʻe o nā saponins a me nā mea anti-nutritional ʻē aʻe e hoʻoulu ai i ka enteritis subacute o ka ʻōpū distal i loko o kēia mau iʻa he nui. Hōʻike ʻia kēia kūlana e ka hoʻonui ʻia ʻana o ka permeability ʻōpū, ka mumū, a me nā ʻano ʻē aʻe o ke ʻano e alakaʻi ana i ka emi ʻana o ka pono o ka hānai a me ka ulu ʻana i hoʻopilikia ʻia.

I loko o ka iʻa ʻōʻō anuenue, me ka SBM ma luna o 20% o ka meaʻai ua hōʻike ʻia e hoʻoulu i ka soy-enteritis, e kau ana i kahi paepae physiological ma ka pae hiki ke pani ʻia i loko o kahi meaʻai aquaculture maʻamau. Ua nānā mua ʻia nā noiʻi i kekahi mau ʻano hana e hakakā ai i kēia enteritis, me ka hoʻopunipuni ʻana i ka microbiome gut, ka hana ʻana i nā mea hoʻohui e wehe i nā mea anti-nutritional, a me nā mea hoʻohui antioxidant a me probiotic. ʻO kahi ala i ʻimi ʻole ʻia ʻo ka hoʻokomo ʻana o ka trimethylamine oxide (TMAO) i nā meaʻai aquaculture. ʻO TMAO kahi cytoprotectant honua, i hōʻiliʻili ʻia i loko o nā ʻano he nui e like me ka protein a me ka membrane stabilizer. Maanei, hoʻāʻo mākou i ka hiki o TMAO ke hoʻoikaika i ka paʻa o ka enterocyte a kāohi i ka hōʻailona inflammatory HSP70 ma laila e hakakā ai i ka enteritis i hoʻokomo ʻia e ka soy a alakaʻi i ka hoʻonui ʻana i ka pono o ka hānai, ka paʻa ʻana a me ka ulu ʻana i ka iʻa ʻōʻō anuenue wai maʻemaʻe. Eia hou, nānā mākou inā hiki ke hoʻohana ʻia nā mea hoʻoheheʻe iʻa kai, kahi kumu waiwai o TMAO, ma ke ʻano he ala kūpono no ka hoʻokele waiwai ʻana i kēia mea hoʻohui, e hiki ai ke hoʻohana ʻia ma ke ʻano he ʻano hana waiwai no ka hoʻokele ʻana i kēia mea hoʻohui, e hiki ai ke hoʻohana ʻia ma ke ʻano kalepa.

Ua mālama ʻia ka iʻa ʻōniʻoniʻo i mahi ʻia (Troutlodge Inc.) ma ke kaumaha mua awelika o 40 g a me n=15 no kēlā me kēia pahu i loko o nā pahu mālama ʻekolu. Ua hānai ʻia nā pahu i kekahi o nā ʻai ʻeono i hoʻomākaukau ʻia ma ke kumu meaʻai digestible e hāʻawi ana i ka 40% protein digestible, 15% momona maka, a me ka hoʻokō ʻana i nā ʻano waikawa amino kūpono. ʻO nā ʻai i hoʻokomo ʻia i ka mana iʻa 40 (% o ka ʻai maloʻo), SBM 40, SBM 40 + TMAO 3 g kg^-1, SBM 40 + TMAO 10 g kg^-1, SBM 40 + TMAO 30 g kg^-1, a me SBM 40 + 10% iʻa hiki ke hoʻoheheʻe ʻia. Ua hānai ʻia nā pahu i ʻelua manawa i ka lā a hiki i ka māʻona ʻana no 12 mau pule a ua hana ʻia nā loiloi fecal, proximate, histological a me molecular.

E kūkākūkā ʻia nā hopena o kēia noiʻi a me ka pono o ka hoʻokomo ʻana iā TMAO e hiki ai ke hoʻohana nui ʻia nā huahana soy US i nā mea hānai salmonid.