ʻAka Guanylacetic, i kapa ʻia ʻo guanylacetic acid, he amino acid analogue i hana ʻia mai ka glycine a me L-lysine.

Hiki i ka Guanylacetic acid ke synthesize i ka creatine ma lalo o ka catalysis o nā enzymes a ʻo ia wale nō ka mea e pono ai no ka synthesis o ka creatine. ʻIke ʻia ʻo Creatine ma ke ʻano he mea hoʻolale ikehu, a ʻo kāna hana nui ka hana ʻana i ka creatine phosphorylated ma lalo o ka hana a ka creatine kinase.

E komo i ka huakaʻi adenosinepōʻai hosphate (ATP). Ke lawa ʻole ka ikehu ATP, hoʻololi koke ka phosphocreatine i ka pūʻulu phosphate i adenosine diphosphate ma o ka creatine kinase a hoʻohuli hou i ka adenosine triphosphate.

 

Hoʻohana i nā ruminants:

Hoʻohui i ka 0.12%, 0.08%, a me 0.04% guanylacetic acid i ka ʻai o 120 barn hānai Tan hipa kaumaha ma kahi o 20 kilokani, i hōʻike ʻia i ka hoʻohui ʻana o 0.12% a me 0.08% guanylacetic acid i hoʻonui nui ʻia i kēlā me kēia lā ke kaumaha o ke kaumaha, intramuscular momona a me ka nui o ka momona maʻiʻo.

 

ʻO ka hoʻohui o 0.08%ʻakika guanylaceticua hoʻonui ʻia ka pākēneka ʻiʻo ma ka 9.77%. Ma ka hoʻohana ʻana i ke ʻano hana hana kinoea in vitro, ua aʻo ʻia ka hopena o ka hoʻohui ʻana i nā pae like ʻole o ka guanylacetic acid ma ka rumen o nā pipi melemele. Ua ʻike ʻia ʻo ka hoʻohui ʻana o 0.4% guanylacetic acid i hoʻonui nui ʻia i ka hana kinoea, a ua hoʻonui mua ka neʻe ʻana o ka amonia nitrogen a laila hoʻemi.

No laila, hiki ke hoʻomaopopo ʻia ʻo ka hoʻohui ʻana i ka waikona guanylacetic i ka hānai ʻana i kēlā me kēia lā hiki ke hoʻomaikaʻi i ke ʻano o ka rumen i loko a me ke ʻano fermentation o nā pipi melemele.

Hoʻohana i ka moa:

ʻO ka hoʻohui ʻana i ka 800 mg/kg, 1600 mg/kg, 4000 mg/kg, a me 8000 mg/kg o ka guanylacetic acid i ka hānai ʻana i kēlā me kēia lā o nā broilers ua hōʻike ʻia ʻo ka hoʻohui ʻana i ka 800-4000 mg/kg o ka guanylacetic acid i ka hānai i hoʻonui nui i ka loaʻa ʻana o ke kaumaha o kēlā me kēia lā o nā broilers, hoʻemi i ka hānai broil i 2 mau lā o ke kaumaha. ʻO ka hoʻohui ʻana i ka 8000 mg/kg o ka guanylacetic acid i hoʻomaikaʻi i ka serum biochemical indicators e like me ka urea nitrogen, nā hōʻailona maʻamau o ke koko, a me ka bilirubin piha ʻAʻohe hopena koʻikoʻi i nā hōʻailona o ke kino nui, e hōʻike ana i ka hoʻohui ʻana i ka 8000 mg/kg o ka guanylacetic acid i ka meaʻai i kēlā me kēia lā o nā broilers hiki ke ʻae ʻia.

ʻO ka hoʻohui ʻana i ka 200 mg / kg, 400 mg / kg, 600 mg / kg, a me 800 mg / kg o ka guanylacetic acid i ka hānai broiler ua hōʻike i ka piʻi nui o ka loaʻa ʻana o ke kaumaha o kēlā me kēia lā ke hoʻohālikelike ʻia me ka pūʻulu mana. Loaʻa nā hopena maikaʻi loa i ka wā o nā pae hoʻohui i 600 a me 800 mg / kg.

No ke aʻo ʻana i ka hopena o ka waikawa guanylacetic ma ka maikaʻi o ka sperm i nā moa, ua koho ʻia nā moa he 20 28 wiki e hānai i kahi meaʻai i loaʻa ka 0%, 0.06%, 0.12%, a me 0.18% guanylacetic acid. Ua ʻike ʻia nā hopena noiʻi ʻo ka hoʻohui ʻana i ka 0.12% guanylacetic acid i ka meaʻai i hoʻonui nui i ka helu o ka sperm, ka nui o ka semen, a me ka hana sperm i loko o nā moa, e hōʻike ana i ka hoʻohui ʻana i ka waikawa guanylacetic i ka meaʻai hiki ke hoʻomaikaʻi maikaʻi i ka maikaʻi o ka sperm. E hoʻohui i ka 0.0314%, 0.0628%, 0.0942%, a me 0.1256% guanylacetic acid i ka hānai ʻana i kēlā me kēia lā o nā broilers, a hoʻonoho i ʻelua pūʻulu hoʻomalu (ʻo ka pūʻulu mana 1 kahi hānai mea kanu me ka ʻole o nā mea i hoʻohui ʻia, a ʻo ka pūʻulu mana 2 he hānai me ka ʻai iʻa i hoʻohui ʻia). ʻO nā pūʻulu ʻeono ma luna o nā meaʻai i kēlā me kēia lā i like ka pae o ka ikehu a me nā minela.

Hōʻike nā hopena hoʻokolohua ʻoi aku ka kiʻekiʻe o ka loaʻa ʻana o ke kaumaha o nā hui ʻehā me ka guanylacetic acid i hoʻohui ʻia a me ka pūʻulu mana 2 ma mua o ka hui mana 1, ʻO ka pūʻulu mana 2 i loaʻa ka hopena paona maikaʻi loa, ukali ʻia e ka hui 0.0942% guanylacetic acid; ʻO ka pūʻulu mana 2 ka mea maikaʻi loa i ka ratio paona, a ukali ʻia e ka hui 0.1256% guanylacetic acid.

Hoʻohana i ka moa:

Hoʻohui 800 mg/kg, 1600 mg/kg, 4000 mg/kg, a me 8000 mg/kg oʻakika guanylacetici ka meaʻai i kēlā me kēia lā o nā broilers hōʻike i ka hoʻohui ʻana i ka 800-4000 mg / kg o ka guanylacetic acid i ka hānai i hoʻonui nui ʻia i ka loaʻa ʻana o ke kaumaha i kēlā me kēia lā o nā broilers, ua hoʻemi i ka hānai ʻana i ke kaumaha o nā broilers ma 22-42 mau lā o ka makahiki. ʻO ka hoʻohui ʻana i ka 8000 mg/kg o ka guanylacetic acid i hoʻomaikaʻi i ka serum biochemical indicators e like me ka urea nitrogen, nā hōʻailona maʻamau o ke koko, a me ka bilirubin piha ʻAʻohe hopena koʻikoʻi i nā hōʻailona o ke kino nui, e hōʻike ana i ka hoʻohui ʻana i ka 8000 mg/kg o ka guanylacetic acid i ka meaʻai i kēlā me kēia lā o nā broilers hiki ke ʻae ʻia. ʻO ka hoʻohui ʻana i ka 200 mg / kg, 400 mg / kg, 600 mg / kg, a me 800 mg / kg o ka guanylacetic acid i ka hānai broiler ua hōʻike i ka piʻi nui o ka loaʻa ʻana o ke kaumaha o kēlā me kēia lā ke hoʻohālikelike ʻia me ka pūʻulu mana. Loaʻa nā hopena maikaʻi loa i ka wā o nā pae hoʻohui i 600 a me 800 mg / kg.

No ke aʻo ʻana i ka hopena o ka waikawa guanylacetic ma ka maikaʻi o ka sperm i nā moa, ua koho ʻia nā moa he 20 28 wiki e hānai i kahi meaʻai i loaʻa ka 0%, 0.06%, 0.12%, a me 0.18% guanylacetic acid. Ua ʻike ʻia nā hopena noiʻi ʻo ka hoʻohui ʻana i ka 0.12% guanylacetic acid i ka meaʻai i hoʻonui nui i ka helu o ka sperm, ka nui o ka semen, a me ka hana sperm i loko o nā moa, e hōʻike ana i ka hoʻohui ʻana i ka waikawa guanylacetic i ka meaʻai hiki ke hoʻomaikaʻi maikaʻi i ka maikaʻi o ka sperm. E hoʻohui i ka 0.0314%, 0.0628%, 0.0942%, a me 0.1256% guanylacetic acid i ka hānai ʻana i kēlā me kēia lā o nā broilers, a hoʻonoho i ʻelua pūʻulu hoʻomalu (ʻo ka pūʻulu mana 1 kahi hānai mea kanu me ka ʻole o nā mea i hoʻohui ʻia, a ʻo ka pūʻulu mana 2 he hānai me ka ʻai iʻa i hoʻohui ʻia). ʻO nā pūʻulu ʻeono ma luna o nā meaʻai i kēlā me kēia lā i like ka pae o ka ikehu a me nā minela. Hōʻike nā hopena hoʻokolohua ʻoi aku ka kiʻekiʻe o ka loaʻa ʻana o ke kaumaha o nā hui ʻehā me ka guanylacetic acid i hoʻohui ʻia a me ka pūʻulu mana 2 ma mua o ka hui mana 1.ʻakika guanylacetichui; ʻO ka pūʻulu mana 2 ka mea maikaʻi loa i ka ratio paona, a ukali ʻia e ka hui 0.1256% guanylacetic acid.