ʻO ka hoʻohana akamai ʻana o nā mea hoʻohui hānai hou-Glycerol Monolaurate i ka mahiʻai aqua

I nā makahiki i hala iho nei, ua loaʻa i nā glycerides o MCFA, ma ke ʻano he ʻano mea hoʻohui hānai hou, ka nānā nui ʻia ma muli o kā lākou hana antibacterial kiʻekiʻe a me nā hopena maikaʻi i ke olakino ʻōpū.ʻO Glycerol monolaurate (GML) he monoester MCFA meaʻai i loaʻa i ka waiū umauma a me ka ʻaila niu. Ua ʻae ka FDA ua manaʻo ʻia he palekana ia ke hoʻohana ʻia ma kahi pae mahele o 10 a 2000mg/kg i nā huahana like ʻole. Ma waho aʻe o kona hopena antibacterial a me antiviral, loaʻa iā ia nā waiwai emulsifying.

ʻO Glycerol Monolaurate（CASNo：142-18-7）

 Inoa：ʻO Glycerol Monolaurate

Inoa ʻē aʻe：Monolaurin a i ʻole GML

 Fʻōmula：C₁₅H₃₀O₄

kaumaha molekala：274.21

ka hiki ke hoʻoheheʻe ʻia：Hoʻoheheʻe iki ʻia i ka waia me ka glycerol,hiki ke hoʻoheheʻe ʻia i loko o ka methanol, ka etanol

helehelena：Paʻa keʻokeʻo a melemele māmā paha

Loaʻa i ka GML ka hiki ke noho i loko o ke ala ʻai no ka manawa lōʻihi a hoʻomaikaʻi i nā ʻōpū, ʻo ia hoʻi hiki i ka GML ke hoʻopili pololei i ka microbiome o ka ʻōpū, e kōkua ana i ke kino e hōʻiliʻili i nā meaolaola i hiki ʻole ke omo ʻia a hoʻonui hope i ka hiki o ke kino ke omo i ka ikehu.

A hiki i kēia lā, ua aʻo hohonu ʻia nā hopena hoʻoulu ulu a me nā hopena immunomodulatory o nā monoglycerides i loko o nā manu e hoʻonui i ka nui o ka hana hua manu, ka pono o ka hānai ʻana, ka maikaʻi o ka hua manu hou a me ka waiwai o ka meaʻai o nā manu. Eia kekahi, he hopena hoʻolaha olakino ko GML a me nā hana anti-inflammatory a me antibacterial ikaika.

Nā hopena o ka monoglyceride laurate (GML) ma ka hana ulu ʻana, nā enzyme digestive, ke ʻano o ke kino a me ka pane pale ʻole kikoʻī o Litopenaeus vannamei.

2. Ua hānai ʻia ka ʻōpae i hoʻohana ʻia ma ke aʻo ʻana me ʻehā mau meaʻai like ʻole, me 0, 350, 700 a me 1050mg/kg GML i hoʻohui ʻia i nā meaʻai. Ua mau ka hoʻokolohua no 60 mau lā.

Ua hōʻike ʻia nā hopena noiʻi e hoʻomaikaʻi nui ana ʻo GML 700 a me 1050 mg/kg i ka hana ulu ʻana, nā hana lipase ʻōpū a me nā protease, ʻoiai ʻo ka hoʻohui ʻana o GML 1050 mg/kg i ka meaʻai e hoʻonui ai i nā lipids serum a me nā lipids maka systemic.

Ua hōʻike ʻia nā hana o ka lipase ʻōpū a me ka protease i kahi ʻano piʻi me ka loli o nā pae GML, a ʻo nā hui GML ma nā hui mahele 700 a me 1050 mg/kg ua ʻoi aku ke kiʻekiʻe ma mua o ka hui kaohi (P < 0.05). I kēia manawa, ʻaʻohe hopena koʻikoʻi o nā pae like ʻole o GML i ka hana o nā enzyme digestive i loko o ka hepatopancreas.

Eia kekahi, ke hoʻohui ʻia ʻo GML i ka meaʻai ma nā nui o 350 a me 700mg/kg, hoʻonui ia i ka palekana o ka ʻōpae ma ka hoʻomaikaʻi ʻana i ko lākou kūlana antioxidant a me antibacterial.

ʻO ka hiki o ka GML haʻahaʻa ma ke ʻano he mea hoʻohui hānai e hoʻomaikaʻi i ka ulu ʻana, ka hana enzyme digestive a me ka pale ʻole kikoʻī o ka ʻōpae keʻokeʻo. Wahi a nā hopena noiʻi, ma muli o ka hoʻonui ʻia o nā hana o ka lipase intestinal a me ka protease, ua hoʻomaikaʻi nui nā dosis hoʻohui hānai o 700 a me 1050 mg/kg GML i ka hana ulu ʻana o ka ʻōpae keʻokeʻo mai ʻAmelika Hema.