Potasiuma formate, ka mea hoʻohui hānai ʻaʻohe antibiotic mua i ʻāpono ʻia e ka ʻAhahui ʻEulopa i ka makahiki 2001 a ua ʻāpono ʻia e ke Kuhina Mahiʻai o Kina i ka makahiki 2005, ua hōʻiliʻili i kahi hoʻolālā noi makua no nā makahiki he 10 a ʻoi, a ua hōʻike nā pepa noiʻi he nui ma ka home a me ka honua i kona hopena ma nā pae like ʻole o ka ulu ʻana o ka puaʻa.

ʻO ka necrotizing enteritis kahi maʻi manu honua i hoʻokumu ʻia e ka bacteria gram-positive (Clostridium perfringens), kahi e hoʻonui ai i ka make o nā broilers a hoʻemi i ka hana ulu o nā moa ma ke ʻano subclinical. Hoʻopilikia kēia mau hopena ʻelua i ka pono o nā holoholona a lawe mai i nā pohō waiwai nui i ka hana moa. I ka hana maoli, hoʻohui pinepine ʻia nā antibiotics i ka meaʻai e pale aku i ka hanana o ka necrotizing enteritis. Eia nō naʻe, ke piʻi nei ke kāhea no ka pāpā ʻana i nā antibiotics i ka meaʻai, a pono nā hoʻonā ʻē aʻe e pani i ka hopena pale o nā antibiotics. Ua ʻike ʻia ka noiʻi ʻana ʻo ka hoʻohui ʻana i nā waikawa organik a i ʻole ko lākou paʻakai i ka meaʻai e hiki ke kāohi i ka ʻike o Clostridium perfringens, a laila e hōʻemi ana i ka hanana o ka necrotizing enteritis. Hoʻopau ʻia ka potassium formate i loko o ka waikawa formic a me ka potassium formate i loko o ka ʻōpū. Ma muli o ka waiwai pili covalent i ka mahana, ua komo piha kekahi waikawa formic i loko o ka ʻōpū. Ua hoʻohana kēia hoʻokolohua i ka moa i loaʻa i ka necrotizing enteritis ma ke ʻano he kumu hoʻohālike noiʻi e noiʻi i nā hopena opotassium formatema luna o kāna hana ulu, ka microbiota ʻōpū, a me ka nui o nā waikawa momona kaulahao pōkole.

1. Ka Hopena oPotasiuma Diformatema ka hana ulu ʻana o nā broilers i loaʻa i ka maʻi Necrotizing Enteritis.

Ua hōʻike ʻia nā hopena hoʻokolohua ʻaʻohe hopena koʻikoʻi o ka potassium formate i ka ulu ʻana o nā broilers me ka maʻi necrotizing enteritis a i ʻole me ka ʻole, kahi e kūlike me nā hopena noiʻi a Hernandez et al. (2006). Ua ʻike ʻia ʻaʻohe hopena koʻikoʻi o ka nui like o ka calcium formate i ka loaʻa ʻana o ke kaumaha o kēlā me kēia lā a me ka lakio hānai o nā broilers, akā i ka wā i hiki ai ka hoʻohui ʻana o ka calcium formate i 15 g/kg, ua hoʻemi nui ia i ka ulu ʻana o nā broilers (Patten lāua ʻo Waldroup, 1988). Eia naʻe, ua ʻike ʻo Selle et al. (2004) ʻo ka hoʻohui ʻana i 6 g/kg o ka potassium formate i ka ʻai ua hoʻonui nui i ka loaʻa ʻana o ke kaumaha a me ka lawe ʻana i ka hānai o nā moa broiler ma 16-35 mau lā. I kēia manawa he kakaikahi nā hōʻike noiʻi e pili ana i ke kuleana o nā waikawa organik i ka pale ʻana i ka maʻi necrotizing enteritis. Ua ʻike ʻia kēia hoʻokolohua ʻo ka hoʻohui ʻana i 4 g/kg potassium formate i ka ʻai ua hoʻemi nui i ka nui o ka make ʻana o nā broilers, akā ʻaʻohe pilina hopena-dose ma waena o ka emi ʻana o ka nui o ka make a me ka nui o ka potassium formate i hoʻohui ʻia.

2. Hopena oPotasiuma Diformatema ka ʻike Microbial i loko o nā ʻiʻo a me nā ʻōpū o nā Broilers i loaʻa i ka maʻi Necrotizing Enteritis

ʻO ka hoʻohui ʻana o 45mg/kg bacitracin zinc i ka hānai i hoʻemi i ka make ʻana o nā broilers i loaʻa i ka necrotizing enteritis, a i ka manawa like i hoʻemi i ka nui o Clostridium perfringens i loko o ka jejunum, kahi i kūlike me nā hopena noiʻi a Kocher et al. (2004). ʻAʻohe hopena koʻikoʻi o ka hoʻohui ʻana o ka potassium diformate i ka nui o Clostridium perfringens i loko o ka jejunum o nā broilers i loaʻa i ka necrotizing enteritis no 15 mau lā. Ua ʻike ʻo Walsh et al. (2004) he hopena maikaʻi ʻole nā ​​​​meaʻai acidity kiʻekiʻe i nā waikawa organik, no laila, ʻo ka acidity kiʻekiʻe o nā meaʻai protein kiʻekiʻe e hōʻemi i ka hopena pale o ka potassium formate i ka necrotizing enteritis. Ua ʻike pū kēia hoʻokolohua ua hoʻonui ka potassium formate i ka nui o lactobacilli i loko o ka ʻōpū ʻiʻo o nā moa broiler 35d, kahi mea kūlike ʻole me Knarreborg et al. (2002) i loaʻa i loko o vitro ua hoʻemi ka potassium formate i ka ulu ʻana o lactobacilli i loko o ka ʻōpū puaʻa.

3.Ka hopena o ka potassium 3-dimethylformate ma ka pH kiko a me ka nui o ka waikawa momona kaulahao pōkole i nā moa broiler i loaʻa i ka necrotizing enteritis

Ua manaʻo ʻia ʻo ka hopena antibacterial o nā waikawa organik e hana nui ʻia ma ka ʻaoʻao o luna o ke ala ʻai. Ua hōʻike nā hopena o kēia hoʻokolohua ua hoʻonui ka potassium dicarboxylate i ka nui o ka waikawa formic i loko o ka duodenum i 15 mau lā a me ka jejunum i 35 mau lā. Ua ʻike ʻo Mroz (2005) he nui nā mea e hoʻopilikia ai i ka hana o nā waikawa organik, e like me ka pH hānai, buffering/acidity, a me ke kaulike electrolyte meaʻai. ʻO ka acidity haʻahaʻa a me nā waiwai kaulike electrolyte kiʻekiʻe i ka meaʻai hiki ke hoʻolaha i ka dissociation o ka potassium formate i loko o ka waikawa formic a me ka potassium formate. No laila, ʻo kahi pae kūpono o ka acidity a me nā waiwai kaulike electrolyte i ka meaʻai hiki ke hoʻonui i ka hoʻomaikaʻi ʻana i ka hana ulu o nā broilers e ka potassium formate a me kona hopena pale i ka necrotizing enteritis.

Hopena

Nā hopena opotassium formateMa ke kumu hoʻohālike o ka necrotizing enteritis i nā moa broiler ua hōʻike ʻia hiki i ka potassium formate ke hōʻoluʻolu i ka emi ʻana o ka hana ulu o nā moa broiler ma lalo o kekahi mau kūlana ma o ka hoʻonui ʻana i ke kaumaha o ke kino a me ka hōʻemi ʻana i ka make, a hiki ke hoʻohana ʻia ma ke ʻano he mea hoʻohui hānai e kāohi i ka maʻi o ka necrotizing enteritis i nā moa broiler.