I nā makahiki i hala iho nei, ua nui aʻe nā "pāʻina mea hoʻohui" i puka mai i loko o ka ʻoihana mālama ʻili. ʻAʻole lākou e hoʻolohe hou i nā hoʻolaha a me nā mea kākau blog nani e kanu ana i ka mauʻu i ko lākou makemake, akā e aʻo a hoʻomaopopo i nā mea hoʻohui pono o nā huahana mālama ʻili iā lākou iho, i mea e koho ai i nā huahana mālama ʻili kūpono no lākou.

Me ka hoʻokūkū ikaika ma waena o nā lama mālama ʻili, ʻoi aku ka nui o nā lama e alualu ana i nā "mea hoʻohui hou aku" i nā "mea hoʻohui pono". ʻOi aku ka kaulana o nā mea mālama ʻili i kākoʻo ʻia e ka ʻenehana ʻeleʻele, e hana ana i kahi kūlana e "nānā ka ʻaoʻao mea hoʻohui mua i nā mea hoʻohui, a nānā ka ʻaoʻao mea hoʻohui kiʻekiʻe i ka ʻenehana".

E makaʻala i nā huahana hou o nā lama poʻo kūloko a me nā haole, a ʻike ʻia e wikiwiki ana kēia mau lama poʻo i ka hoʻomaikaʻi ʻana i nā mea maka a me ka ʻenehana, i hiki ai i nā huahana hou ke huki i nā mea kūʻai aku, a hiki i ka ʻenehana hou ke alakaʻi i ka ʻoihana e komo i kahi ala hou. ʻO ka piʻi ʻana o ka ʻepekema a me ka ʻenehana he hōʻailona ia o ka hoʻoikaika ʻana i ka hoʻopili kūloko no nā mea hoʻomaʻamaʻa hoʻonaninani.

Hōʻike ka hōʻike nānā 2025 e pili ana i ka hoʻopili ʻana o ka ʻepekema a me ka ʻenehana i ka ʻoihana nani e ulu hohonu ana ka hoʻohui ʻana o ka nani a me ka ʻenehana, a e hoʻomau ka ʻenehana holomua e pili ana i ka ʻepekema olaola i ke kōkua ʻana i ka R&D a me ka hana ʻana i nā huahana nani hou. ʻO ka ʻoihana nani i hiki i ka ʻepekema a me ka ʻenehana e hoʻolauna i kahi pahū, a e hiki aku ka pae mākeke ma kahi o 1 trillion yuan ma ka makahiki 2025.

 

Ua lilo ka noiʻi a me ka hoʻomohala ʻana i nā hoʻomākaukau nanopharmaceutical i ke kuhikuhi nui o ke kaiāulu lapaʻau a me ka lāʻau lapaʻau o kēia manawa, a ua paipai ʻia a kākoʻo ʻia ka hoʻohana ʻana i nā ʻano hana hou o nā liposomes a me nā vesicles pharmaceutical e like me ka ʻenehana nano carrier i nā mea hoʻonani hana.

Ma muli o ka paʻakikī o ke komo ʻana o ka epidermis kanaka, paʻakikī ka hiki ʻana aku i ka ʻili hohonu o ka ʻili i ka meaʻai, kahi e hoʻopilikia nui ai i ka hopena o ka hoʻohana ʻana i nā huahana mālama ʻili. Ua puka mai ka ʻenehana Nanocarrier e like me ka manawa e pono ai, ʻo ia hoʻi ka hoʻoponopono ʻana i nā pilikia o ka lawe ʻana i kuhikuhi ʻia, ka hoʻokuʻu lohi ʻana i ka lāʻau, ka absorption transdermal a pēlā aku. ʻO nā nanocarriers i hoʻohana pinepine ʻia e komo pū me nā liposomes, nā mea lawe hydrogel, nā micelles, nā microcapsules, nā ʻōnaehana kristal wai, nā supramolecules, a pēlā aku.

ʻO ka hoʻohana ʻana i nā nanocarriers e hāʻawi i nā mea hoʻohui pono o ka mālama ʻili i loko o nā wahi a me nā cell i manaʻo ʻia no ka mālama ʻili ma o ka lawe ʻana i ka ʻili, hoʻokuʻu lohi a lōʻihi ka lōʻihi, e hoʻoponopono pono ana i ka pilikia loea maʻamau o ka ʻoihana o nā mea hoʻonani pono kuʻuna i paʻakikī ke komo ma o ka ʻili. Loaʻa i nā Nanocarriers nā hana o ka hoʻomaikaʻi ʻana i ka solubility a me ka dispersibility wai o nā mea hana o nā mea hoʻonani insoluble, hoʻomaikaʻi i ke kūpaʻa o nā mea hana issensitive light a me ka wela, a hoʻomaikaʻi i ka hoʻohālikelike ʻana o nā mea hana.

I ka makahiki 1965, ua ʻike nā kānaka ʻepekema Pelekane ʻo Bangham lāua ʻo Standish hiki i nā phospholipids ke hana koke i nā vesicles bilayer (micelle) i loko o ka wai ma o ka microscopy electron, a kapa iā lākou he liposomes. Ua lilo kēia i hoʻokahi o nā ʻike nui i ka ʻoihana lāʻau lapaʻau i ke kenekulia 20.

ʻO ka momi ma ka lei aliʻi o nā nanocarriers -- liposomes

ʻOiai ʻo ke ʻano kumu o ka membrane plasma biological he membrane bilayer phospholipid hoʻi, he ʻano like ko nā liposomes me nā cell biological, no laila he biocompatibility maikaʻi ko lākou, no laila ua kapa ʻia lākou ʻo "artificial biofilm". Hoʻohana nā liposomes i kēia kūlike e hoʻokō i ka lawe ʻana i ka lāʻau lapaʻau i kuhikuhi ʻia a kūpono paha. Pono nā liposomes kūpono e loaʻa ka histocompatibility maikaʻi, haʻahaʻa ka ʻawaʻawa, kūpono ka encapsulation lāʻau lapaʻau a me ka hiki ke hoʻokuʻu.

E like me ka inoa e hōʻike nei, ʻo ka ʻāpana nui o nā liposomes he "lipids". ʻO nā liposomes maʻamau i hana ʻia me nā phospholipids a me ka cholesterol, he mau mea endogenous ia e noho ana i loko o nā meaola, he kūpono maikaʻi me nā ʻiʻo a ʻaʻole immunogenic.

ʻO ka hoʻolālā mea maka i hoʻopilikino ʻia no nā liposomes

Inoa kālepa o ka mea maka: pale aku i ka liposome ʻelemakule

ʻO ka hoʻolālā encapsulation hui: liposome + retinol + astaxanthin + coenzyme Q10

Ka pono o nā mea maka: kū paʻa a kū i ka wrinkle

Ka hoʻohana ʻana i manaʻo ʻia: 5% - 10%

Nā huahana pili: Wai ʻano, ʻano, pale maka, gel, lotion, kirīmi