No nā makahiki he ʻumi, ua hoʻohana ʻia ka waikawa butyric i ka ʻoihana hānai holoholona e hoʻomaikaʻi i ke olakino ʻōpū a me ka hana holoholona. Ua hoʻolauna ʻia kekahi mau hanauna hou e hoʻomaikaʻi i ka lawelawe ʻana i ka huahana a me kāna hana mai ka wā i hana ʻia ai nā hoʻokolohua mua i nā makahiki 80.

No nā makahiki he ʻumi, ua hoʻohana ʻia ka waikawa butyric i ka ʻoihana hānai e hoʻomaikaʻi i ke olakino ʻōpū a me ka hana holoholona. Ua hoʻolauna ʻia kekahi mau hanauna hou e hoʻomaikaʻi i ka lawelawe ʻana i ka huahana a me kāna hana mai ka wā i hana ʻia ai nā hoʻokolohua mua i nā makahiki 80..

1. Ka hoʻomohala ʻana o ka waikawa butyric ma ke ʻano he mea hoʻohui hānai

1980s > Hoʻohana ʻia ka waikawa Butyric e hoʻomaikaʻi i ka ulu ʻana o ka rumen

1990s> nā paʻakai o ka waikawa butyrin i hoʻohana ʻia no ka hoʻomaikaʻi ʻana i ka hana holoholona

2000s> ua hoʻomohala ʻia nā paʻakai i uhi ʻia: ʻoi aku ka maikaʻi o ka loaʻa ʻana o ka ʻōpū a me ka emi ʻana o ka ʻala

2010s> Ua hoʻolauna ʻia kahi waikawa butyric esterified hou a ʻoi aku ka maikaʻi

I kēia lā, ua noho aliʻi ʻia ka mākeke e ka waikawa butyric i pale maikaʻi ʻia. ʻAʻohe pilikia o nā mea hana hānai e hana pū ana me kēia mau mea hoʻohui me nā pilikia ʻala a ʻoi aku ka maikaʻi o ka hopena o nā mea hoʻohui i ke olakino a me ka hana o ka ʻōpū. Eia nō naʻe, ʻo ka pilikia me nā huahana i uhi ʻia maʻamau ka haʻahaʻa o ka waikawa butyric. ʻO ka maʻamau, loaʻa i nā paʻakai i uhi ʻia he 25-30% butyric acid, he haʻahaʻa loa ia.

ʻO ka hoʻomohala hou loa i nā mea hoʻohui hānai i hoʻokumu ʻia i ka waikawa butyric ʻo ia ka hoʻomohala ʻana o ProPhorce™ SR: glycerol esters o ka waikawa butyric. Hiki ke loaʻa maoli kēia mau triglycerides o ka waikawa butyric i ka waiū a me ka meli. ʻO lākou ke kumu kūpono loa o ka waikawa butyric i pale ʻia me ka nui o ka waikawa butyric a hiki i ka 85%. Loaʻa iā Glycerol kahi e loaʻa ai ʻekolu mau molekala waikawa butyric i hoʻopili ʻia iā ia ma o nā mea i kapa ʻia ʻo 'ester bond'. Loaʻa kēia mau pilina ikaika i nā triglycerides āpau a hiki ke uhaki wale ʻia e nā enzymes kikoʻī (lipase). I loko o ka hua a me ka ʻōpū e noho paʻa ana ka tributyrin a ma ka ʻōpū kahi e loaʻa koke ai ka pancreatic lipase i hoʻokuʻu ʻia ka waikawa butyric.

Ua hōʻoia ʻia ke ʻano hana o ka esterifying butyric acid ʻo ia ke ala kūpono loa e hana ai i ka waikawa butyric ʻala ʻole e hoʻokuʻu ʻia ma kahi āu e makemake ai: i loko o ka ʻōpū.

Hana Tributyrin

1.Hoʻoponopono i nā villi ʻōpū liʻiliʻi o nā holoholona a pale i nā bacteria ʻino o ka ʻōpū.

2.Hoʻomaikaʻi i ka omo ʻana a me ka hoʻohana ʻana i nā meaʻai.

3.Hiki ke hōʻemi i ka maʻi pākī a me ke kaumaha o nā holoholona ʻōpio i ka wā e hānai ai.

4.Hoʻonui i ka nui o ke ola a me ka loaʻa ʻana o ke kaumaha o kēlā me kēia lā o nā holoholona ʻōpio.