2. Glyceryl butyrate

He ʻala ʻoluʻolu ʻole ka waikawa butyric a he maʻalahi hoʻi e hoʻoheheʻe, a he paʻakikī ke hiki i ka hopena hope o ka ʻōpū e pāʻani i kahi hana ma hope o ka ʻai ʻia ʻana e nā holoholona, ​​​​no laila ʻaʻole hiki ke hoʻohana pololei ʻia i ka hana ʻana. ʻO Glyceryl butyrate ka huahana momona o ka waikawa butyric a me ka glycerin. Hoʻopaʻa ʻia ka waikawa butyric a me ka glycerin e nā pilina covalent. He paʻa lākou mai ka pH1-7 a i 230 ℃. Ma hope o ka ʻai ʻia ʻana e nā holoholona, ​​​​ʻaʻole e pala ka glyceryl butyrate i loko o ka ʻōpū, akā pala i ka waikawa butyric a me ka glycerin i loko o ka ʻōpū ma lalo o ka hana a ka pancreatic lipase, e hoʻokuʻu mālie ana i ka waikawa butyric. ʻO Glyceryl butyrate, ma ke ʻano he mea hoʻohui hānai, he maʻalahi ke hoʻohana, palekana, ʻaʻohe ʻawaʻawa, a he ʻono kūikawā. ʻAʻole ia e hoʻoponopono wale i ka pilikia he paʻakikī ke hoʻohui i ka waikawa butyric ma ke ʻano he wai a he ʻala ʻino, akā hoʻomaikaʻi pū kekahi i ka pilikia he paʻakikī ke hiki i ka waikawa butyric i ke ala ʻōpū ke hoʻohana pololei ʻia. Ua manaʻo ʻia ʻo ia kekahi o nā huahana butyric acid maikaʻi loa a me nā huahana anti histamine.

2.1 ʻO Glyceryl Tributyrate a me Glyceryl Monobutyrate

ʻO TributyrinʻO 3 mau molekala o ka waikawa butyric a me 1 molekala o ka glycerol ka mea e hoʻokuʻu mālie ai ʻo Tributyrin i ka waikawa butyric i loko o ka ʻōpū ma o ka pancreatic lipase, kahi hapa i hoʻokuʻu ʻia ma ke alo o ka ʻōpū, a hiki i kahi hapa ke hiki i ke kua o ka ʻōpū e pāʻani i kahi hana; Hoʻokumu ʻia ka monobutyric acid glyceride e hoʻokahi molekala o ka waikawa butyric e hoʻopaʻa ana i ka pūnaewele mua o ka glycerol (pūnaewele Sn-1), nona nā waiwai hydrophilic a me lipophilic. Hiki iā ia ke hiki i ka hopena hope o ka ʻōpū me ka wai digestive. Hoʻokuʻu ʻia kekahi waikawa butyric e ka pancreatic lipase, a ua komo pololei kekahi e nā cell epithelial ʻōpū. Hoʻoheheʻe ʻia i loko o ka waikawa butyric a me ka glycerol i loko o nā cell mucosal ʻōpū, e paipai ana i ka ulu ʻana o ka villi ʻōpū. Loaʻa iā Glyceryl butyrate ka polarity molecular a me ka nonpolarity, hiki ke komo pono i ka membrane paia cell hydrophilic a lipophilic paha o nā bacteria pathogenic nui, e hoʻouka i nā cell bacteria, e luku i ke ʻano o ke kelepona, a pepehi i nā bacteria ʻino. Loaʻa i ka monobutyric acid glyceride kahi hopena antibacterial ikaika i nā bacteria gram-positive a me nā bacteria gram-negative, a he hopena antibacterial maikaʻi aʻe.

2.2 Hoʻohana ʻia ʻana o ka glyceryl butyrate i nā huahana wai

ʻO Glyceryl butyrate, ma ke ʻano he derivative o ka waikawa butyric, hiki ke hoʻokuʻu pono i ka waikawa butyric ma lalo o ka hana a ka lipase pancreatic ʻōpū, a ʻaʻohe ona ʻala, paʻa, palekana a ʻaʻohe koena. ʻO ia kekahi o nā koho maikaʻi loa i nā antibiotics a hoʻohana nui ʻia i ka aquaculture. Ua hōʻike ʻo Zhai Qiuling et al. i ka wā i hoʻohui ʻia ai ka 100-150 mg/kg tributylglycerol ester i ka meaʻai, hiki ke hoʻonui nui ʻia ka nui o ke kaumaha, ka nui o ka ulu ʻana, nā hana o nā enzyme digestive like ʻole a me ke kiʻekiʻe o ka villi ʻōpū ma mua a ma hope o ka hoʻohui ʻana o 100 mg/kg tributylglycerol ester; Ua ʻike ʻo Tang Qifeng a me nā mea noiʻi ʻē aʻe e hiki i ka hoʻohui ʻana i ka 1.5g/kg tributylglycerol ester i ka meaʻai ke hoʻomaikaʻi nui i ka hana ulu o Penaeus vannamei, a hoʻemi nui i ka helu o nā vibrio pathogenic i loko o ka ʻōpū; Jiang Yingying et al. ua ʻike ʻia ʻo ka hoʻohui ʻana i ka 1g/kg o ka tributyl glyceride i ka meaʻai hiki ke hoʻonui nui i ka nui o ke kaumaha o ka Allogynogenetic crucian carp, e hōʻemi i ka coefficient hānai, a hoʻonui i ka hana o ka superoxide dismutase (SOD) i loko o ka hepatopancreas; Ua hōʻike kekahi mau haʻawina ʻo ka hoʻohui ʻana o 1000 mg/kgʻO ka tributyl glyceridei ka meaʻai hiki ke hoʻonui nui i ka hana intestinal superoxide dismutase (SOD) o Jian carp.