Ua hoʻohana ʻia nā ʻakika momona pōkole, me ka butyrate a me nā ʻano mea i loaʻa mai, i mea hoʻohui meaʻai e hoʻohuli a hoʻomaikaʻi paha i nā hopena maikaʻi ʻole o nā mea kanu i loaʻa i nā mea kanu i loko o nā meaʻai iʻa, a loaʻa i ka nui o nā hopena physiological a me ke olakino hoʻomaikaʻi maikaʻi i nā mammals a me nā holoholona. Ua helu ʻia ʻo Tributyrin, kahi ʻakika butyric i hoʻohui ʻia i nā meaʻai o nā holoholona mahiʻai, me nā hopena hoʻohiki i kekahi mau ʻano. I nā iʻa a me nā crustaceans, ʻoi aku ka hou o ka hoʻokomo ʻana i ka tributyrin i ka meaʻai a ʻaʻole i aʻo ʻia akā ʻike ʻia nā hopena he mea maikaʻi loa ia no nā holoholona wai. He mea koʻikoʻi kēia no nā ʻano mea ʻai ʻai, pono e hoʻomaikaʻi maikaʻi ʻia nā meaʻai no ka hōʻemi ʻana i ka ʻai iʻa i mea e hoʻoikaika ai i ka hoʻomau kaiapuni a me ka hoʻokele waiwai o ka ʻāpana. Hōʻike ka hana i kēia manawa i ka tributyrin a hōʻike i nā hopena nui o kāna hoʻohana ʻana ma ke ʻano he kumu meaʻai o ka waikawa butyric i nā meaʻai no nā ʻano wai. Hāʻawi ʻia ka manaʻo nui i nā ʻano iʻa aʻoaʻo a pehea e hiki ai i ka tributyrin, ma ke ʻano he meaʻai meaʻai, ke kōkua i ka hoʻomaikaʻi ʻana i nā aquafeeds.
2. Glyceryl butyrate
He ʻala maikaʻi ʻole ka Butyric acid a maʻalahi hoʻi i ka volatilize, a he paʻakikī ke hiki i ka hope o ka ʻōpū e pāʻani i kahi kuleana ma hope o ka ʻai ʻia ʻana e nā holoholona, no laila ʻaʻole hiki ke hoʻohana pololei ʻia i ka hana. ʻO Glyceryl butyrate ka huahana momona o ka waikawa butyric a me ka glycerin. Hoʻopaʻa ʻia ka ʻakika Butyric a me ka glycerin e nā paʻa covalent. Paʻa lākou mai ka pH1-7 a i ka 230 ℃. Ma hope o ka ʻai ʻia ʻana e nā holoholona, ʻaʻole decompose ka glyceryl butyrate i loko o ka ʻōpū, akā decomposes i loko o ka waikawa butyric a me ka glycerin i loko o ka ʻōpū ma lalo o ka hana a ka pancreatic lipase, e hoʻokuʻu mālie i ka waikawa butyric. ʻO Glyceryl butyrate, ma ke ʻano he meaʻai meaʻai, maʻalahi e hoʻohana, palekana, ʻaʻohe mea ʻawaʻawa, a he ʻono kūikawā. ʻAʻole wale ia e hoʻonā i ka pilikia he paʻakikī ka paʻakikī o ka butyric acid e hoʻohui ʻia ma ke ʻano he wai a honi ʻino, akā hoʻomaikaʻi pū i ka pilikia e paʻakikī ai ka butyric acid i ka ʻāpana ʻōpū ke hoʻohana pololei ʻia. Manaʻo ʻia ʻo ia kekahi o nā derivatives butyric acid maikaʻi loa a me nā huahana anti histamine.
2.1 Glyceryl Tributyrate a me Glyceryl Monobutyrate
TributyrinAia i loko o 3 mau mole o ka butyric acid a me 1 mole o ka glycerol. Hoʻokuʻu mālie ʻo Tributyrin i ka waikawa butyric i loko o ka ʻōpū ma o ka pancreatic lipase, kahi i hoʻokuʻu ʻia ma ke alo o ka ʻōpū, a hiki i kahi ʻāpana ke hiki i ke kua o ka ʻōpū e pāʻani i kahi kuleana; Hoʻokumu ʻia ka monobutyric acid glyceride e hoʻokahi mole o ka waikawa butyric e paʻa ana i ka pae mua o ka glycerol (Sn-1 site), nona nā waiwai hydrophilic a me lipophilic. Hiki iā ia ke hōʻea i ka hope o ka ʻōpū me ka wai hoʻoheheʻe. Hoʻokuʻu ʻia kekahi ʻakika butyric e ka pancreatic lipase, a hoʻopili pololei ʻia kekahi e nā cell epithelial intestinal. Ua decomposed i butyric acid a me ka glycerol i loko o ka intestinal mucosal cell, e paipai ana i ka ulu ana o intestinal villi. He molecular polarity a me ka nonpolarity ʻo Glyceryl butyrate, hiki iā ia ke komo pono i ka membrane hydrophilic a lipophilic cell wall o ka bacteria pathogenic nui, hoʻouka i nā cell bacteria, luku i ke ʻano o ka cell, a pepehi i nā maʻi ʻino. He hopena antibacterial ikaika ko Monobutyric acid glyceride i ka hua bacteria gram-positive a me gram-negative bacteria, a ʻoi aku ka maikaʻi o ka hopena antibacterial.
2.2 Ka hoʻohana ʻana i ka glyceryl butyrate i nā huahana wai
ʻO Glyceryl butyrate, ma ke ʻano he derivative o ka butyric acid, hiki ke hoʻokuʻu maikaʻi i ka waikawa butyric ma lalo o ka hana o ka lipase pancreatic intestinal, a ʻaʻohe ʻala, kūpaʻa, palekana a me ke koena manuahi. ʻO ia kekahi o nā mea koho maikaʻi loa i nā lāʻau antibiotic a hoʻohana nui ʻia i ka iʻa. Zhai Qiuling et al. hōʻike i ka wā i hoʻohui ʻia ai ka 100-150 mg / kg tributylglycerol ester i ka hānai, hiki ke hoʻonui nui ʻia ka nui o ke kaumaha, ka nui o ka ulu ʻana, nā hana o nā enzyme digestive like ʻole a me ke kiʻekiʻe o ka intestinal villi ma mua a ma hope o ka hoʻohui ʻana o 100 mg / kg tributylglycerol ester; Uaʻikeʻo Tang Qifeng a me nā mea noiʻi'ē aʻe i ka hoʻonuiʻana i ka 1.5g / kg tributylglycerol ester i ka hānai hiki ke hoʻonui i ka hana ulu o Penaeus vannamei, a hoʻemi nui i ka helu o nā vibrio pathogenic i loko o ka'ōpū; ʻO Jiang Yingying et al. ʻike ʻia ʻo ka hoʻohui ʻana i ka 1g/kg o ka tributyl glyceride i ka hānai hiki ke hoʻonui nui i ka nui o ke kaumaha o Allogynogenetic crucian carp, hoʻemi i ka coefficient hānai, a hoʻonui i ka hana o ka superoxide dismutase (SOD) i ka hepatopancreas; Ua hōʻike kekahi mau haʻawina i ka hoʻohui ʻana o 1000 mg / kgtributyl glyceridei ka meaʻai hiki ke hoʻonui nui i ka hana o ka intestinal superoxide dismutase (SOD) o Jian carp.
Ka manawa hoʻouna: Jan-05-2023
